A new promising treatment in systemic sclerosis: 5-fluorouracil.
نویسندگان
چکیده
Twelve patients with systemic sclerosis according to American Rheumatism Association criteria were treated with intravenous 5-fluorouracil. Significant subjective and objective improvement occurred initially in the skin and subsequently in the involved viscera and vasculature. These preliminary results suggest that 5-fluorouracil may be an effective treatment for systemic sclerosis.
منابع مشابه
Sarcoidosis or primary Sjögren's syndrome?
1 Casas J A, Subauste C P, Alarc6n G S. A new promising treatment in systemic sclerosis: 5-fluorouracil. Ann Rheum Dis 1987; 46: 763-7. 2 Calabresi P, Parks R E Jr. Chemotherapy of neoplastic diseases. In: Gilman A G, Goodman L S, Rall T W, Murad F, eds. Goodman and Gilman's the pharmacological basis of therapeutics. 7th ed. New York: Macmillan, 1985: 1240-306. 3 Physicians' Desk Reference (PDR...
متن کاملاثر درمانی آلپروستادیل بر زخم انگشتان در مبتلایان به اسکلرودرمی: گزارش موردی از یک درمان جدید
ABSTRACT Systemic sclerosis is a disease with skin tightness. Besides of skin involvement, there may be involvement of different organs. Systemic sclerosis may be diffuse or limited, but in both of them Raynoud’s phenomen is common. This phenomen is due to vasoconstriction and vascular insufficiency and is a phenomen that makes problem for the patient and does not have any efficient treatment....
متن کاملEffects of Ultrasound Irradiation on the Release Profile of 5-fluorouracil from Magnetic Polylactic co-glycolic Acid Nanocapsules
Background: Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency.Objective: Here, we studies the effects of ultrasound irradiation on the release profile of 5-flu...
متن کاملEfficacy of 5-Fluorouracil plus Epinephrine, Pulsed Dye Laser and Betamethasone on the Improvement of Psoriatic Plaques (A Comparative Study)
Background: Many efforts are made to find new and more effective treatments for psoriasis. Intralesional 5-Fluorouracil (5-FU) +epinephrine is a cheap option which can be administered with long intervals. The effectiveness of Pulse Dye Laser (PDL) on psoriasis has been already assessed. We decided to evaluate the effectiveness of 5-FU+epinephrine and compare it to betamethasone and PDL.</...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 46 10 شماره
صفحات -
تاریخ انتشار 1987